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(a) Mean increases in hind-footpad thickness for C3H mice infected with wild-type (WT) and Δicp3[pXG ICP] promastigotes. (b) The parasites in the footpad were quantified by limiting dilution for up to 2 weeks postinfection, and the effects of intraperitoneal anti-IFN-γ treatment (150 μg rat hybridoma R4-6A2 on day 0, day 4, and day 8) on the growth of Δicp3[pXG ICP] were assessed. Bars represent standard errors of the means. Results are representative of two independent experiments.
