FIG. 6.
Mean increases in hind-footpad diameter (a and b) and parasite burdens (c and d) following subcutaneous infection with 5 × 105 wild-type L. mexicana stationary-phase promastigotes into naïve (▪) C3H mice (a and c) and C57BL/6 mice (b and d) and mice vaccinated with 2 × 105 stationary-phase Δicp1[pXG ICP] (□) or Δicp3[pXG ICP] (•) promastigotes (a, b, c, and d). Mean levels of IFN-γ production from antigen-stimulated splenocytes isolated from wild-type-L. mexicana-infected naïve C3H (e) and C57BL/6 (f) mice and mice vaccinated with Δicp1[pXG ICP] or Δicp3[pXG ICP] stationary-phase promastigotes. *, P < 0.05; **, P < 0.01. Bars represent standard errors of the means. Results are representative of two independent experiments.