FIG. 2.

Gene arrangement of the group W135 cps cluster. Regions show the various functional groups within the cluster, as follows: region B (lipid modification genes), region D′ (duplicate LOS biosynthesis operon), region E (putative regulator), region C (capsule transport genes), region A (capsule biosynthesis operon), and region D (LOS biosynthesis operon). Underlined sections represent sequence data collected during the course of this study. Localization of the genes identified with comparative genome hybridizations between the group W135 and group C variants are also identified. NMC0051 and NMC0050 are involved with biosynthesis and O acetylation of the capsule, respectively, and were expected to differ. NMC0038 (NMB0054) and NMC0073 (NMB0088) are located outside the region sequenced (underlined), and further analysis found there to be significant sequence differences in the genes of the two variant strains. The locations marked with a filled star signify the SOR found in a previous study (21).