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. 2009 Apr 13;77(7):3004–3013. doi: 10.1128/IAI.01114-08

FIG. 5.

FIG. 5.

(A) Bacterial loads in the spleens of Igh6−/− mice after serum transfer. Igh6−/− mice were inoculated i.p. with a 1:1 mixture of WT and virB mutant bacteria. Serum from naive Igh6−/− mice, naïve C57BL/6, or immunized C57BL/6 mice was transferred intravenously into 10 Igh6−/− mice per group at days 5, 11, and 17 after infection. CFU were recovered from the spleens 21 days after infection. The significance of differences (P < 0.05) between the virB mutant and the WT was determined by Student's t test. (B) Bacterial loads in the spleens of Igh6−/− mice after IgG transfer. Igh6−/− mice were inoculated i.p. with a 1:1 mixture of WT and virB mutant bacteria. IgG purified from naïve or immunized C57BL/6 mice was transferred intravenously into five Igh6−/− mice per group at days 5, 11, and 17 after infection. CFU from the spleens were enumerated 21 days after infection. The significance of differences (P < 0.05) between the virB mutant and the WT was determined by Student's t test.