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. 2009 May 18;77(7):2857–2865. doi: 10.1128/IAI.01355-08

FIG. 4.

FIG. 4.

PAK ΔfliC inhibits Pam3CSK4-stimulated NF-κB activation. NF-κB-luc-expressing Calu-3 cells were incubated for 4 h with 10−6 g/ml flagellin or 0.1 or 1.0 μg/ml Pam3CSK4 and/or 108 CFU/ml PAK ΔfliC in the combinations shown. Luciferase activation was expressed as a percentage of the maximal (Max) stimulation caused by flagellin in any experiment, and average percentages (± standard deviations) were plotted. n = 3 for all data. The symbol # indicates significant difference from the value measured for cells without treatment. The symbol * indicates significant difference in comparison to treatment with Pam3CSK4-treated versus Pam3CSK4-plus-PAK ΔfliC-treated cells. Values for flagellin versus flagellin plus either concentration of PAM3CSK4 were not statistically significantly different from each other.