FIG. 7.

NOD1 controls growth of L. monocytogenes in murine embryonic fibroblasts and astrocytes. NOD1^−/− and WT fibroblasts (A and B) and astrocytes (C) in triplicate wells were incubated with L. monocytogenes at multiplicities of infection (MOI) of 30 (A), 0.3 (B), and 10 (C) and lysed at the indicated time points after infection. The numbers of L. monocytogenes CFU in the cell lysates were determined. *, P < 0.05 for a comparison with WT mice (Student's t test), indicating a significant difference. SEM, standard error of the mean.