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. 2000 Sep 12;97(20):10701–10705. doi: 10.1073/pnas.170297297

Figure 2.

Figure 2

Natural conservation of mutated 4-4-20 residues. Comparison of occurrence frequencies in mouse VH and VL κ genes of wild-type (abscissa) and mutation (ordinate) amino acid identities are shown. Frequencies were calculated at mutated sequence positions from statistics in the Kabat database (25).