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. 2009 May 13;83(15):7619–7628. doi: 10.1128/JVI.00470-09

FIG. 1.

FIG. 1.

Vaccination of pigtail macaques with recombinant influenza virus-SIV. Two naïve pigtail macaques expressing the Mane-A*10 allele were vaccinated twice with recombinant 108 PFU influenza A virus (H1N1 influenza virus KP9, PR8 strain) 4 weeks apart. (A) Recovery of influenza virus RNA from respiratory swabs by qRT-PCR. (B) Seroconversion to influenza A virus by hemagglutination inhibition (HI). (C) Detection of SIV Gag KP9-specific CD8 T cells in blood by KP9/Mane-A*10 tetramer staining. The proportion of all CD8 T cells staining for the KP9/Mane-A*10 tetramer is shown.