. 2009 May 13;83(15):7619–7628. doi: 10.1128/JVI.00470-09

TABLE 1.

Animals studied and influenza virus-specific T-cell epitopes identified

SIV infection status	Influenza virus-SIV vaccination regimen	Animal no.	SIV Gag KP9 response (%) postvaccination^a	Influenza virus epitope(s) mapped^b
SIV infection status	Influenza virus-SIV vaccination regimen	Animal no.	SIV Gag KP9 response (%) postvaccination^a	CD4	CD8
Uninfected, naïve	Day 0, H1N1-KP9; day 28, H1N1-KP9; day 300, H3N2-KP9; day 328, H3N2-KP9	1335	0.06	M1_91-107	NP_401-423^c
Uninfected, naïve		2374	0.04	NP_401-423
SIV infected	Day 0, H1N1-KP9; day 28, H1N1-KP9; day 98, H3N2-KP9; day 126, H3N2-KP9	5821	8.78	NP_466-482, NP_300-362^d, M1_36-57, M1_51-112^d	NP_401-423
		5827	10.22	NP_186-202, M1_36-57, NP_300-362^d, NP_401-462^d	NP_311-332, NP_456-472, NP_482-498 M1_41-62, M1_86-107
		086B	3.79	NP_151-212^d, NP_300-362^d	NP_401-423, NP_151-212^d
		8305	0.48	NP_401-423
	Day 0, H3N2-KP9; day 28, H3N2-KP9; day 77, H1N1-KP9; day 105, H1N1-KP9	8454^e	0.74	NP_300-362^d, NP_186-202	NP_451-498^d
		9017^e	0.57
		9020^e	0.11
		1.3731^e	0.47	NP_451-498^d, M1_86-107
	Day 0, H1N1-KP9, H1N1-KSA10, H1N1-KVA10	5612	8.74	Not done	Not done

Peak CD8 T-cell response determined by KP9/Mane-A*10 tetramer, expressed as percentage of all CD8 T cells.

Common epitopes identified are in bold.

The NP_401-423 response was mapped to minimal epitope NP_402-410 (SAGQISIQP, SP9) as shown in Fig. 4B.

Pool of 10 overlapping peptides, not finely mapped.

Studied only for responses to epitopes already mapped in animals 5821, 5827, 086B, and 8305.