FIG. 8.

The peak depletion rate of CD4⁺ T cells coincides with the peak production of virus in the compartment. Shown is modeling of CD4⁺ T-cell depletion using the same parameters as in Fig. 7c but showing viral production from each compartment. The solid lines represent CD4⁺ T cells in each compartment, with circles at the maximum rates of loss of CD4⁺ T cells. The dotted lines represent the contributions of each compartment to the total viral load.