Relative to normal homogenates, soluble Axl is significantly increased in chronic silent tissue homogenates, soluble Mer is significantly increased in chronic active, and full-length Mer is significantly increased in chronic silent tissue homogenates. A–E: The relative densitometric intensity was determined for each band and normalized to β-actin. Average values for full-length Axl (A), Mer (B), and Tyro3 (C), and average values for soluble Axl (D) and Mer (E) in chronic active, OND, normal, and chronic silent brain tissue homogenates are shown. Significance was tested by Student’s t-test between chronic active or chronic silent, and normal tissue homogenates; *P < 0.05, **P < 0.01.