Figure 2.

Representative pictures of NOLC1 protein staining in different NPC biopsy specimens. A–B: Type I NPC biopsy specimens. C–F: Type III NPC biopsy specimens. The paraffin sections were stained with either monoclonal anti-NOLC1 (A, C–E) or the control IgG (B, F). The NOLC1 immunoreactivity was seen clearly in the nucleoli of the tumor cell (arrows) in the tumor nests, but not in the stromal cells or in the normal squamous metaplastic epithelial cells (C, arrowhead). No reaction product was seen in the control sections. S: stromal cells; T: tumor nest; L: lymphocyte. Scale bars = 25 μm (A, B, D–F); 5 μm (C).