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E2F1 overexpression in Saos2 cells raises anti-tumor barriers. A: Addition of 400 nmol/L 4-OH-Tamoxifen leads to nuclear translocation of E2F1. B: Growth curves of Saos2 E2F1-ER cells with and without the addition of 4-OH-Tamoxifen (4-OH-Tam). The lines are the means of three independent experiments. C: Percentage of apoptotic cells as determined by fluorescence-activated cell sorting analysis. The lines are the means of three independent experiments.
