FIGURE 3.
Helical wheel diagram of the N-terminal region (residues 14–29) of human PTHrP, PTH, and the homologue, Tip39, a hypothalamic ligand for PTH2R (29, 33). Strictly conserved residues are highlighted in red, and conservative substitutions are in green. The shaded region denotes the helical face that interacts with both antibody and receptor.