FIGURE 5.
Inhibition of CRM1 during DENV-2 infection of Vero cells increases nuclear accumulation of NS5, but not capsid protein. A, CLSM images of fixed mock- and DENV-2-infected Vero cells immunostained for NS5 and capsid protein (C) at the indicated time points post-infection and treated with or without LMB. Quantitative analysis to determine Fn/c values for NS5 (B) and Fn/c and Fnu/c values for capsid protein (C) was performed as described in the legend to Fig. 2. Results represent the means ± S.E., where significant differences (p values) are indicated between LMB-treated and untreated cells (n ≥ 48).