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Summary of the binding experiments with the FH19–20 mutants
Arrows pointing up indicate increase in binding and arrows pointing down decrease in binding; horizontal arrows indicate no change in the binding when compared to the wild-type FH19–20.
The asterisks indicate: * According to aHUS database (www.fh-hus.org). ** Published in Jokirantaet al.2006. *** Reduced binding to C3b, wild-type-like binding to C3d.
