TABLE 1.
Wnt-5a, but notWnt-7a, affects specifically the postsynaptic protein PSD-95 without affecting the presynaptic protein Synaptophysin
Quantification of PSD-95 and synaptophysin clusters in 100 μm of neurite length of hippocampal neurons 14 DIV exposed to different treatments (n = 3).
Treatment | PSD-95 clustering | Synaptophysin clustering |
---|---|---|
number/100 μm neurite | number/100 μm neurite | |
pcDNA | 59.67 ± 7.72 | 45.32 ± 8.93 |
Wnt-7a | 64.17 ± 10.03 | 86.07 ± 16.35a |
Wnt-5a | 110.72 ± 19.01a | 48.79 ± 12.16 |
ap< 0.01.