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. 2009 Apr 7;284(23):15993–16003. doi: 10.1074/jbc.M901144200

FIGURE 6.

FIGURE 6.

A CXCR4 inhibitor abrogated Notch activation-promoted DC maturation. DCs were cultured from normal BM cells in the presence or absence of hDll1DSL. The CXCR4 inhibitor AMD3100 was added as indicated. Cells were cultured for 9 days and analyzed by FACS. A, CD11c+ DCs were plotted for SSC and forward scattering. B, the number of CD11c+ DCs in R1 and R2 was calculated and compared. C, expression of MHC II was analyzed by FACS. Bars represent means ± S.D. (n = 5). **, p < 0.01.