Table 2.
Subject demographics
| Prepubertal (n = 184) | Early pubertal (n = 197) | Late pubertal (n = 58) | P valuea | |
|---|---|---|---|---|
| Age (yr) | 9.0 ± 1.5 | 11.0 ± 1.4 | 13.7 ± 1.7 | <0.001b |
| Weight (kg) | 29.7 ± 7.9 | 40.7 ± 9.6 | 53.9 ± 12.2 | <0.001b |
| Serum 25-OHD (nmol/liter) | 95 ± 33 | 80 ± 28 | 75 ± 30 | <0.001c |
| Calcium intake (mg/d) | 1093 ± 245 | 1039 ± 324 | 952 ± 279 | 0.004d |
| Total Ca-abs (mg/d) | 324 ± 115 | 344 ± 158 | 292 ± 136 | 0.04e |
| Ca-abs fraction | 0.301 ± 0.90 | 0.330 ± 0.102 | 0.314 ± 0.124 | 0.02f |
| Urinary calcium (mg/kg · d) | 2.8 ± 2.0 | 2.2 ± 1.5 | 2.0 ± 1.2 | 0.001g |
| Alkaline phosphatase activity (IU/liter) | 227 ± 58 | 266 ± 75 | 176 ± 100 | <0.001b |
All data are mean ± sd.
a
Shown are overall P values. Subsequent pairwise comparisons were performed after adjustment by Fisher’s least significant differences for multiple comparisons. Significant pairwise comparisons (P < 0.05) are noted as below.
b
Each pairwise comparison (P < 0.001).
c
Pairwise comparison: pre- vs. early pubertal and pre- vs. late pubertal (P < 0.001).
d
Pairwise comparison: pre- vs. late pubertal (P = 0.001), early vs. late pubertal (P = 0.04).
e
Pairwise comparison: early vs. late pubertal (P = 0.01).
f
Pairwise comparison: early vs. prepubertal (P = 0.005).
g
Pairwise comparison: pre- vs. early pubertal (P = 0.004), pre- vs. late pubertal (P = 0002).