Table 1.
Characteristics of women with POI (n = 442) and concurrent controls (n = 70)
| POI | Control | P value | |
|---|---|---|---|
| Demographics | |||
| Age (yr)a | 32.3 (5.5) | 30.1 (7.2) | <0.01 |
| Race, n (%) | 0.02 | ||
| White | 348 (79) | 50 (71) | |
| African-American | 48 (11) | 11 (16) | |
| Asian | 18 (4) | 8 (11) | |
| Hispanic | 28 (6) | 1 (1) | |
| Height (cm)a | 164.9 (7.2) | 164.4 (6.0) | 0.67 |
| Weight (kg)a | 66.4 (13.3) | 62.3 (10.1) | 0.04 |
| BMI (kg/m2)a | 24.4 (4.6) | 22.9 (2.8) | 0.04 |
| Reproductive characteristics | |||
| Age at menarche (yr)a | 12.8 (1.5) | 12.7 (1.3) | 0.72 |
| Nulligravida, n (%) | 290 (66) | 35 (50) | 0.02 |
| Nullipara, n (%) | 358 (81) | 40 (57) | <0.0001 |
| FSH (IU/liter)a | 75.3 (39.9) | 6.3 (2.0) | <0.0001 |
| LH (IU/liter)a | 47.6 (24.6) | 7.9 (5.8) | <0.0001 |
| Estradiol (pg/ml)a | 46.9 (53.5) | 102.7 (97.2) | <0.0001 |
| Free testosterone (pg/ml)a | 2.5 (1.3) | 3.5 (1.5) | <0.0001 |
a
Data are reported as mean (sd).