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. Author manuscript; available in PMC: 2009 Jul 10.
Published in final edited form as: Biochim Biophys Acta. 2007 Feb 20;1770(6):927–932. doi: 10.1016/j.bbagen.2007.02.002

Figure 1. GRP/BBS treatment induces S-phase progression and PI3K-regulated BrdU incorporation in neuroblastoma cells.

Figure 1

(A) SK-N-SH cells were serum starved for 24 h prior to treatment with GRP for 16 h. GRP caused an increase in the S and G2/M phases, in comparison to control cells. (B) SK-N-SH cells were serum starved for 24 h prior to treatment with BBS and/or LY294002 over a time course (24-72 h). BBS induced BrdU incorporation at 48 and 72 h; this response was blocked significantly with LY294002. Data represent mean ± SEM; * p < 0.05 vs. control.