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. Author manuscript; available in PMC: 2009 Jul 10.
Published in final edited form as: Biochim Biophys Acta. 2007 Feb 20;1770(6):927–932. doi: 10.1016/j.bbagen.2007.02.002

Figure 4. Knockdown of GRP receptor inhibits PI3K activation.

Figure 4

(A) BE(2)-C cells were transfected with siGRPR or siNTC. Protein was collected 72 h post-transfection. Knockdown of GRP receptor caused a decrease in BBS-induced Akt phosphorylation. (B, C) SK-N-SH and LAN-1 cells also demonstrated decrease in phospho-Akt by siGRPR. Values under blots represent protein fold-change levels (relative to respective β-actin) in comparison to control lane.