Table 4.
Outcome assessment and reporting for 20 included clinical trials of probiotics for IBS
|
Outcome |
||||||||
| Reference | Global response | Abdominal pain | Bloating/distension | Flatulence | Stool frequency | Mucous | Stool consistency | Dyspepsia |
| Maupas[45] | R | R | R | R | R | R | ||
| Gade[46] | R | R | R | R | R | |||
| Halpern[47] | R | A | A | A | A | A | ||
| Nobaek[48] | R | R | R | A | R | |||
| O’Sullivan[49] | R | R | A | R | A | |||
| Niedzielin[50] | R | R | R | A | A | |||
| Kim[51] | R | R | R | R | R | R | ||
| Bausserman[52] | A | R | R | A | A | |||
| Bittner[53] | A | A | A | |||||
| Kajander[54] | R | R | R | R | R | A | A | |
| Kim[55] | R | R | R | R | R | |||
| Niv[56] | R | R | R | A | ||||
| O’Mahony[17] | R | R | R | A | R | |||
| Kim[57] | R | A | A | A | A | |||
| Simren[58] | R | A | A | A | A | A | A | |
| Whorwell[35] | R | R | R | R | A | |||
| Enck[59] | R | R | A | A | A | |||
| Gawronska[60] | R | |||||||
| Marteau[61] | R | R | A | A | ||||
| Simren[62] | R | A | A | |||||
| Percent reporting | 65% | 80% | 50% | 40% | 25% | 0 | 30% | 5% |
A: Assessed; R: Reported in sufficient detail to allow extraction of data. Bold font indicates that this was the primary outcome identified by the authors for analysis. If author reported no difference between active and placebo groups for a given symptom, but did provide further details, the outcome was classified as assessed only.