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. 2009 Jul 10;136(15):2633–2642. doi: 10.1242/dev.034439

Fig. 8.

Fig. 8.

Model for the effects of BMP4 on two populations of MGE-derived interneuron precursors. The PV+ and SST+ interneuron precursors (pPV and pSST, respectively) derived from the neural progenitor cells (NPC), migrate tangentially from the MGE to the cortex after downregulation of Olig1/2 and Nkx2.1 expression. BMP4 enhances the differentiation of PV+ interneurons (solid arrow) and inhibits the differentiation of SST+ interneurons (inhibitory bar) from their precursors. The genes expressed in each cell type are indicated.