Table II. Morbidity and mortality of pups derived from biopsied and in vitro cultured embryos.
| Group | Embryos transferred (recipients) | Embryos/recipient (mean ± S.E.) | No. of pups | Micea examined | No. of deaths |
Survival | Miceb examined | No. of deaths |
Survival | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Maternal factors | Unexpected | Ill | Unexpected | ||||||||
| % | % | % | |||||||||
| Biopsied | 225 (17) | 13.2 ± 0.9c | 39 (17.3)c | 39 | 9 | 2 | 71.8c | 19 | 2 | 0 | 89c |
| Control | 98 (7) | 14.0 ± 0.8c | 45 (45.9)d | 44 | 20 | 0 | 54.6d | 22 | 3 | 0 | 86c |
a Nursing pups between 1 and 3 weeks of age.
b Mice bred separately between 4 and 30 weeks of age.
c Values with different superscript letters in the same column are significantly different (p < 0.05).
d Values with different superscript letters in the same column are significantly different (p < 0.05).