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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Arch Biochem Biophys. 2008 Sep 18;480(1):58–67. doi: 10.1016/j.abb.2008.08.024

Figure 3.

Figure 3

Sequence alignment of eukoryotic and prokaryotic mevalonate diphosphate decarboxylases. Alignment was generated using the Bioedit program [36]. Residues selected for mutagenesis are denoted by an asterisk. Numbers above the sequence alignment corresponds to the residues number in human MDD. All sequences were obtained from public databases. Sequences correspond to the following organisms and accession numbers: Homo sapience (human), P53602; Sacchramyces cerevisiae (baker’s yeast), P32377; Rattus norvegicus (rat), Q642E5; Mus musculus (mouse), Q99JF5; Staphylococcus aureus, Q9FD84; Streptococcus pyogenes, Q9FD58; Brachydanio rerio (Zebrafish), 5U403; Trypanosoma brucei, Q388P2; Arabidopsis thaliana(thale cress), 023722; Ginko biloba, Q5UCT8.