Table 2.
Interaction between ICAM5 301 Val>Ile and risk factors on melanoma risk
| Val/Val | Val/Ile | Ile/Ile | ||||
|---|---|---|---|---|---|---|
| Cases/Controls | OR (95%CI) | Cases/Controls | OR (95%CI) | Cases/Controls | OR (95%CI) | |
| Constitutional susceptibility score 1 | ||||||
| Low | 15/12 | 1.00 | 21/28 | 0.83 (0.29, 2.35) | 6/9 | 1.02 (0.25, 4.23) |
| Medium | 13/35 | 0.73 (0.20, 2.68) | 26/34 | 2.15 (0.60, 7.67) | 5/12 | 0.92 (0.19, 4.50) |
| High | 57/21 | 5.73 (1.62, 20.31) | 50/46 | 1.95 (0.58, 6.63) | 20/11 | 3.10 (0.76, 12.62) |
| p for interaction = 0.12 | ||||||
| Cumulative sun exposure with a bathing suit 2 | ||||||
| Low | 14/24 | 1.00 | 16/33 | 1.00 (0.38, 2.66) | 7/9 | 0.98 (0.26, 3.65) |
| Medium | 17/18 | 1.57 (0.57, 4.34) | 22/33 | 1.45 (0.57, 3.68) | 8/10 | 1.96 (0.55, 6.94) |
| High | 38/13 | 4.83 (1.79, 13.06) | 41/29 | 2.30 (0.94, 5.64) | 13/9 | 2.59 (0.76, 8.80) |
| p for interaction = 0.34 | ||||||
1
Unconditional logistic regression adjusted for the matching variables, family history of melanoma, number of lifetime severe sunburns, sunlamp use or tanning salon attendance, cumulative sun exposure while wearing a bathing suit, and geographic region.
2
Unconditional logistic regression adjusted for the matching variables, constitutional susceptibility score, family history of melanoma, number of lifetime severe sunburns, sunlamp use or tanning salon attendance, and geographic region.