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. 2009 Apr 19;284(27):18377–18389. doi: 10.1074/jbc.M109.001503

TABLE 5.

Changes in the mRNA levels from a number of genes in response to Zn2+ deficiency

The gene names are the primary names on Ecogene. The gene descriptions are from Ecogene.

Gene b number Gene product Fold change p value
yodB b1974 Function unknown 2.38 0.0725
zur b4046 Repressor for znuABC, the zinc high affinity transport genes; dimer; binds two Zn(II) ions per monomer 1.37 0.9578
znuC b1858 High affinity ABC transport system for zinc 1.36 0.2294
znuB b1859 High affinity ABC transport system for zinc 1.34 a
zntR b3292 Zinc-responsive activator of zntA transcription 1.34 0.4857
zraS b4003 Two component sensor kinase for ZraP; responsive to Zn2+ and Pb2+; autoregulated; regulation of Hyd-3 activity is probably due to cross-talk of overexpressed protein 1.32 0.1109
zraP b4002 Zinc-binding periplasmic protein; responsive to Zn2+ and Pb2+; regulated by zraSR two-component system; rpoN-dependent 1.25 0.9322
yiiP b3915 Iron and zinc efflux membrane transporter; cation diffusion facilitator family; dimeric 1.17 0.2742
zitB b0752 Zn(II) efflux transporter; zinc-inducible 1.09 0.9571
zntA b3469 Zn(II), Cd(II), and Pb(II) translocating P-type ATPase; mutant is hypersensitive to Zn2+ and Cd2+ salts 1.07 0.9285
spy b1743 Periplasmic protein induced by zinc and envelope stress, part of cpxR and baeSR regulons 1.03 0.8314
zraR b4004 Two component response regulator for zraP; responsive to Zn2+ and Pb2+; autoregulated; regulation of Hyd-3 activity is probably due to cross-talk of overexpressed protein 0.95 0.9315
zupT b3040 Zinc and other divalent cation uptake transporter 0.88 0.3258

a Insufficient data available to obtain a p value.