Table 1.
Comparison of CMR Findings Between Control and DMD Groups
Patient Groups Parameters | A ( n = 16) | B (n = 16) | C (n = 31) | D (n =12) | E (n = 11) |
---|---|---|---|---|---|
Age (years) | 14.5±8.4* | 8.4±0.84* | 13.0±2.9* | 15.8±4.5 | 17.3±5.3 |
Heart Rate (bpm) | 81±15* | 106±15 | 101±16 | 103±6 | 112±19 |
LVM/BSAZ | −2.0±1.2 | −2.0±0.76* | −1.5±0.60 | −0.88±1.7* | 0.46±1.1 |
LVEDV/BSAZ | −2.0±0.96 | −1.6±0.70 | −2.1±1.4 | −0.20±3.9 | 2.6±3.8 |
EDMass/LHT2.7 | 18.5±6.3* | 25.8±5.0 | 26.7±4.2 | 28.8±9.2* | 37±10 |
EF (%) | 65.1±3.7 | 65.5±3.7 | 64.1±5.5* | 47.4±7.4* | 32.7±14.9 |
εcc (%) | −18.6±2.0* | −14.4±1.1* | −12.4±2.1* | −10±1.9* | −6.5±1.2 |
MDE Performed | 0/16 | 7/16 | 26/31 | 10/12 | 11/11 |
MDE Result | --------------- | Negative | Negative | Negative | Negative |
Abbreviations: BPM = beat per minute, CMR = Cardiac Magnetic Resonance Imaging, DMD = Duchenne Muscular Dystrophy, ECG = Electrocardiogram, εcc = Circumferential Strain, EDMass/HT2.7 = Left Ventricular Endiastolic Mass ÷ height2.7, EF = Ejection Fraction, Group A = Control, Group B = DMD age ≤10, Group C = DMD age >10 Normal EF and MDE negative, Group D = DMD age >10 Reduced EF and MDE negative, Group E = DMD age >10 Reduced EF and MDE positive, LVM/BSAZ = Left Ventricular Mass Z-score adjusted to Body Surface Area, LVEDV/BSAZ = Left Ventricular Endiastolic Volume Z-score adjusted to Body Surface Area, MDE = Myocardial Delayed Enhancement, n = Number of patient in each group
P value (<0.05) is significant compared to the preceding group.