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. 2009 Jul 9;15:1332–1350.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Examples of transcripts with different expression patterns related to cataract score. For four selected significantly differentially expressed transcripts, the log intensity ratios are plotted against the cataract score of the respective sample, not taking into account which dietary group the samples belong to. For a certain transcript, if the difference between the mean log intensity ratios of the lenses with a score of 0 and the lenses with a score of 1 was 0.2 or greater, this transcript was classified as “early” regulated. If this difference was less than 0.2, the transcript was classified as “late” regulated. A: SPARC precursor (SPARC; CA052160) was chosen as an example for “early” up-regulated transcripts. B: Metallothionein B (MT-B; CK990996) was chosen as an example of “late” up-regulated transcripts. C: Ependymin (EPN; CA042089) was chosen as an example of “early” down-regulated transcripts. D: Fatty acid binding protein 2 (FABP2; CA054659) was chosen as an example of “late” down-regulated transcripts.