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. Author manuscript; available in PMC: 2010 Apr 28.
Published in final edited form as: Vaccine. 2009 Feb 24;27(19):2616–2624. doi: 10.1016/j.vaccine.2009.02.051

Figure 5.

Figure 5

125I-Botulinum toxin (5 ng) was administered to mice (n=6 per data point), and at various times thereafter animals were sacrificed and blood was collected. The levels of toxin in serum were determined for control mice (■) and for experimental mice that received a neutralizing dose of anti-light chain antibodies (10 μl; ◆). As the Figure illustrates, there was an initial and dramatic reduction in the circulating levels of toxin in mice that received antiserum. This clearance-driven phenomenon occurred within less than 10 min.