Table 3.
Variable | No ESA Use (n = 3143)
|
On ESA Throughout (n = 1823)
|
||||
---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Age (per 10 yr) | 1.57 | 1.46 to 1.70 | <0.001 | 1.53 | 1.41 to 1.65 | <0.001 |
Male | 1.25 | 1.06 to 1.48 | 0.01 | 1.14 | 0.96 to 1.35 | 0.13 |
Diabetes | 1.31 | 1.12 to 1.54 | 0.001 | 0.94 | 0.79 to 1.12 | 0.49 |
GFR (per 5 ml/min) | 0.84 | 0.80 to 0.88 | <0.001 | 0.93 | 0.88 to 0.97 | 0.001 |
Dialysis initiation | 1.94 | 1.58 to 2.38 | <0.001 | 1.70 | 1.37 to 2.11 | <0.001 |
Absolute Hb (intercept; g/L) | 0.99 | 0.980 to 0.993 | <0.001 | 0.99 | 0.980 to 0.993 | <0.001 |
Hb trend (slope; g/L per mo) | 0.96 | 0.93 to 0.99 | 0.013 | 0.94 | 0.92 to 0.97 | <0.001 |
Residual SD (g/L) | 1.03 | 1.02 to 1.05 | <0.001 | 1.02 | 1.01 to 1.04 | 0.008 |
CI, confidence interval; HR, hazard ratio.