Table 1.

Transgenic Reporter Strains and Summary of Results

Strain Name	Inserts	Predictivity
		Aging	Oxygen	Heat
hsp22-GFP(2)1	2	nc [67]	Neg (1) [10]	Neg (1)* [5]
hsp22-GFP(3)1/TM3	1	Neg (2) [74]	Neg (1,2,3) [13]	Nc* [10]
hsp22-GFP(3)1MI1/TM3	2	Neg (3) [56]	Neg (2)* [10]	Nc† [6]
hsp22-DsRed(3)1/TM3	1	ND	Nc† [7]	nc† [4]
hsp70-GFP(3)1 MI2/TM3	2	Neg (2,3) [52]	Nc* [15]	Nc† [10]
hsp70-GFP(3)2/TM3	1	nc [80]	Neg (1) [10]	ND
hsp70-GFP(3)2 MI4/TM3	2	Neg (2,3) [60]	Nc* [8]	Nc† [13]
hsp70-DsRed(3)1 MI2/TM3	2	ND	Nc† [14]	Neg (1)† [12]
PEPCK-GFP	1, >4‡	nc [77]	nc [11]	ND

Notes: The hsp22GFP(2)1 insert is on the second chromosome and is homozygous. The remaining inserts are on the third chromosome and are balanced over TM3, Sb, e. Numbers in parentheses indicate at which of the three time points (TP1, TP2, TP3) a significant negative (Neg) correlation between GFP intensity and subsequent life span was detected by regression analysis (p < .05). ND = assay not done; nc = no significant correlation detected. Certain experiments included less than three time points due to the limited survival of the flies.

^*Experiments that included only two time points (TP1 and TP2).

^†Experiments that included only one time point (TP1).

^‡The PEPCK-GFP reporter flies contain one insert of the PEPCK-GAL4 gene trap and ≥4 inserts of the UAS-GFP construct (materials and methods). The median life span of each cohort is indicated in brackets.