Table 1.

Activity assays of three clones derived from ribozymes self-assembled from RNAs lacking the canonical IGS

Clone	Sequence at Y–Z junction	Relative yield using h•Z substrate (%)
L–30 wild type	… CUAAGGCAU•ACGCUAUGGUGAAGG …	100
1398: Δ4nt	… CUAAGGCAU•[ ]UAUGGUGAAGG …	32
1401: Δ8nt	… CUAAGGCA[ ]CGGUGAAGG …	63
1403: Δ3nt	… CUAAGGCACAU•[ ]UAUGGUGAAGG …	60

Table values are relative transesterification yields after 1 h with the indicated substrate, normalized to that of the V•X•Y•Z construct, set at 100%. Brackets indicate a deletion relative to the wild type.