Figure 5.
Effect of temperature on the formation and dissociation times and on the stability of [TC3]4 (left), [TC4]4 (center) and [TC5]4 (right) at pH 5.1. Upper panels: half formation times (open circles) and dissociation times (black circle) of the fully intercalated tetramers. The half formation times were measured in 10−4 M oligonucleotide solutions or extrapolated at 10−4 M from values measured at higher oligonucleotide concentrations. Lower panels: reduced dissociation constants derived from the monomer and tetramer fractions at equilibrium (black squares).