Table 2.

Mortality rate per 1000 person years, HR (95% CI), and P values for all-cause, cardiovascular, and noncardiovascular mortality in the NECOSAD cohort and HR (95% CI) and P values for all-cause mortality in the Swedish cohort

	CCR5 ins/ins and hsCRP < 10 mg/L (n = 225)	CCR5 ins/ins and hsCRP > 10 mg/L (n = 108)	CCR5Δ32 and hsCRP < 10 mg/L (n = 55)	CCR5Δ32 and hsCRP > 10 mg/L (n = 25)
NECOSAD
All-cause mortality
Mortality rate	91	228	90	133
Crude HR	1	2.55 (1.83 to 3.56)	1.00 (0.60 to 1.65)	1.48 (0.79 to 2.79)
P		<0.01	0.99	0.22
Adjusted HR	1	1.82 (1.29 to 2.58)	0.90 (0.54 to 1.50)	1.39 (0.73 to 2.62)
P		<0.01	0.69	0.32
Cardiovascular mortality
Mortality rate	47	112	52	60
Crude HR	1	2.50 (1.56 to 4.00)	1.11 (0.57 to 2.17)	1.30 (0.51 to 3.31)
P		<0.01	0.76	0.58
Adjusted HR	1	1.85 (1.13 to 3.01)	1.05 (0.53 to 2.07)	1.25 (0.49 to 3.17)
P		0.01	0.89	0.64
Noncardiovascular mortality
Mortality rate	44	116	38	72
Crude HR	1	2.60 (1.62 to 4.19)	0.88 (0.41 to 1.88)	1.67 (0.71 to 3.97)
P		<0.01	0.73	0.24
Adjusted HR	1	1.82 (1.12 to 2.97)	0.76 (0.35 to 1.65)	1.52 (0.64 to 3.63)
P		0.02	0.49	0.34
Swedish	(n = 167)	(n = 79)	(n = 34)	(n = 22)
All-cause mortality
Crude HR	1	2.44 (1.50 to 3.99)	1.50 (0.72 to 3.15)	1.50 (0.66 to 3.40)
P		<0.01	0.28	0.33
Adjusted HR	1	1.67 (1.01 to 2.77)	1.95 (0.91 to 4.19)	0.94 (0.41 to 2.17)
P		0.05	0.09	0.89

Adjusted for gender, age at inclusion, cardiovascular disease, diabetes, and dialysis modality.