Table 4.
NECOSAD and Swedish | CCR5 ins/ins and hsCRP < 10 mg/L (n = 392) | CCR5 ins/ins and hsCRP > 10 mg/L (n = 187) | CCR5Δ32 and hsCRP < 10 mg/L (n = 89) | CCR5Δ32 and hsCRP > 10 mg/L (n = 47) |
---|---|---|---|---|
All-cause mortality | ||||
Crude HR | 1 | 2.46 (1.87 to 3.25) | 1.16 (0.77 to 1.76) | 1.42 (0.86 to 2.34) |
P | <0.01 | 0.49 | 0.17 | |
Adjusted HR | 1 | 1.73 (1.31 to 2.30) | 1.09 (0.72 to 1.66) | 1.23 (0.74 to 2.02) |
P | <0.01 | 0.69 | 0.42 | |
Cardiovascular mortality | ||||
Crude HR | 1 | 2.48 (1.72 to 3.56) | 1.14 (0.66 to 1.98) | 1.36 (0.70 to 2.65) |
P | <0.01 | 0.63 | 0.37 | |
Adjusted HR | 1 | 1.76 (1.21 to 2.54) | 1.16 (0.67 to 2.03) | 1.15 (0.59 to 2.25) |
P | <0.01 | 0.59 | 0.68 | |
Noncardiovascular mortality | ||||
Crude HR | 1 | 2.45 (1.60 to 3.74) | 1.18 (0.63 to 2.23) | 1.50 (0.71 to 3.18) |
P | <0.01 | 0.61 | 0.29 | |
Adjusted HR | 1 | 1.70 (1.10 to 2.62) | 1.03 (0.54 to 1.95) | 1.31 (0.62 to 2.79) |
P | 0.02 | 0.94 | 0.48 |
Adjusted for gender, age at inclusion, cardiovascular disease, diabetes, and dialysis modality.