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. 2009 Jul;20(7):1623–1632. doi: 10.1681/ASN.2008111148

Figure 5.

Figure 5.

CHGA1–40 induces TGF-β-1 secretion from MMCs. Mouse mesangial cells were cocultured (see Concise Methods), with or without a MGENC layer, and incubated with CHGA1–40 (1 μM) for the indicated times. Data are shown as net TGF-β-1 release (CHGA1–40 minus mock stimulation). (A) Total TGF-β-1, by time. Release of total TGF-β-1 was measured at different time points. (B) Active TGF-β-1 at 48 h. Release of active TGF-β-1 was measured at 48 h.