Table 3.
Effect of FR-91 on production of cytokines by peripheral blood mononuclear cells from healthy subjects.
| IL-1β control | IL-1β/FR-91 10 micro | IL-1β/FR-91 25 micro | |
| X | 2.18 ± 0.38 | 2.17 ± 0.34 | 2.33 ± 0.3 |
| IL-2 control | IL-2/FR-91 10 micro | IL-2/FR-91 25 micro | |
| X | 3.94 ± 0.81 | 5.85 ± 1.4 | 9.52 ± 5.66 |
| IL-6 control | IL-6/FR-91 10 micro | IL-6/FR-91 25 micro | |
| X | 4.14 ± 1.58 | 6.5 ± 2.46 | 9.28 ± 4.08* |
| IL-8 control | IL-8/FR-91 10 micro | IL-8/FR-91 25 micro | |
| X | 2.24 ± 0.36 | 2.22 ± 0.38 | 2.3 ± 0.37 |
| IL-10 control | IL-10/FR-91 10 micro | IL-10/FR-91 25 micro | |
| X | 2.3 ± 0.3 | 2.38 ± 0.34 | 2.18 ± 0.4 |
| IL-12 control | IL-12/FR-91 10 micro | IL-12/FR-91 25 micro | |
| X | 3.88 ± 0.55 | 6.73 ± 2.55** | 10.5 ± 4.41** |
| IFN-γ control | IFN-γ/FR-91 10 micro | IFN-γ/FR-91 25 micro | |
| X | 4.18 ± 0.89 | 8.48 ± 4.09* | 15.5 ± 7.76* |
| TNF-α control | TNF-α/FR-91 10 micro | TNF-α/FR-91 25 micro | |
| X | 4.08 ± 0.86 | 7.72 ± 2.43* | 12.5 ± 4.17* |
X: mean ± SD; n = 15; *P < .001; **P < .05.