Figure 1.

Mortality rates, incidence, and severity of arthritis. IL-4-deficient and wt mice were infected with 10⁷ GBS/mouse. Mortality (a), incidence (b), and severity (c) of arthritis were evaluated as detailed in materials and methods (see Section 2). Ten mice were used in each experimental group. (a) The data are the cumulative results of three separate experiments. (b) and (c) Data represent the mean ± SD of three separate experiments. Statistical differences between the experimental groups were marked with asterisk (P < .05).