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. Author manuscript; available in PMC: 2009 Jul 14.
Published in final edited form as: Biochem Pharmacol. 2007 Jan 7;73(9):1499–1510. doi: 10.1016/j.bcp.2007.01.010

Fig. 6.

Fig. 6

DMTU and NAC added after cisplatin treatment suppresses p53 activation and apoptosis in renal tubular cells. RPTC cells were incubated with 20 µM cisplatin for 2 h. Then cisplatin was removed for further 22 h of incubation in the presence or absence of 5 mM DMTU or 0.5 mM NAC. (A) %Apoptosis. (B) Caspase activity. Data are expressed as means ± S.D. (n = 6). *Statistically significantly different from the control group; #significantly different from the cisplatin-only group. (C) Representative blots for p53 and phospho-p53. Whole cell lysates were examined by immunoblot analysis.

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