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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Anesthesiology. 2008 Sep;109(3):502–511. doi: 10.1097/ALN.0b013e318182c26b

Figure 2.

Figure 2

Motor blockade- Dexmedetomidine added to bupivacaine also extended the duration of motor blockade over time when compared to bupivacaine alone. Bupivacaine and bupivacaine plus dexmedetomidine showed improved motor scores when compared with saline and dexmedetomidine. The time course again shows the progression from complete motor blockade (score = 3) to the return of normal motor function (score = 0). Time course data for motor testing were analyzed using a non-parametric model with ordinal logistic regression for repeated measures and generalized estimating equations. Asterisks (*) indicate significant differences for bupivacaine plus dexmedetomidine versus bupivacaine alone at specific times post-injection. † indicates significant differences between dexmedetomidine and saline when compared with bupivacaine plus dexmedetomidine and bupivacaine.