. Author manuscript; available in PMC: 2009 Sep 1.

Published in final edited form as: Anesthesiology. 2008 Sep;109(3):502–511. doi: 10.1097/ALN.0b013e318182c26b

Table 2. Motor scores for bupivacaine and bupivacaine plus dexmedetomidine.

Motor scores (Complete blockade motor score = 3; Normal motor function = 0) were significantly improved at multiple time points when the bupivacaine plus dexmedetomidine group was compared with the bupivacaine group. Time course data for motor testing was analyzed using a non-parametric model with ordinal logistic regression for repeated measures and generalized estimating equations.

Time (min)	Bupivacaine				Bupivacaine + DMET				P value
Time (min)	Mean ± SEM	Median	25^th IQR	75^th IQR	Mean ± SEM	Median	25^th IQR	75^th IQR	P value
30	2.69 ± 0.12	3	2	3	2.94 ± 0.06	3	3	3	NS
60	2.63 ± 0.15	3	2	3	2.94 ± 0.06	3	3	3	NS
90	2.31 ± 0.28	3	1	3	2.94 ± 0.06	3	3	3	0.042
120	2.06 ± 0.32	3	0	3	2.75 ± 0.11	3	2	3	NS
150	1.56 ± 0.32	2	0	3	2.56 ± 0.16	3	2	3	0.002
180	1.31 ± 0.30	1.5	0	2	2.19 ± 0.19	2	2	3	0.01
210	0.94 ± 0.28	0.5	0	2	1.75 ± 0.27	2	1	3	0.01
240	0.81 ± 0.28	0	0	2	1.31 ± 0.27	1	0	2	0.029
270	0.56 ± 0.24	0	0	1	1.00 ± 0.26	1	0	2	0.042
300	0.25 ± 0.11	0	0	0	0.63 ± 0.20	0	0	1	0.038
330	0	0	0	0	0.13 ± 0.09	0	0	0	n/a
360	0	0	0	0	0.13 ± 0.09	0	0	0	n/a
390	0	0	0	0	0.06 ± 0.06	0	0	0	n/a
420	0	0	0	0	0	0	0	0	n/a

DMET = dexmedetomidine; IQR = interquartile range; min = minutes; n/a = not applicable; NS = non-significant; p-value < 0.05 deemed significant; SEM = standard error of mean.