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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Mol Cancer Ther. 2009 Apr;8(4):893–903. doi: 10.1158/1535-7163.MCT-08-1078

Figure 3.

Figure 3

Effect of treatment sequence on the cytotoxicity of TW-37 and cisplatin. A–D, Cells were treated either with single drug alone or both drugs simultaneously for 72 hours or 96 hours. Alternatively, cells were pre-treated for 24 hours with either cisplatin or TW-37. This pre-treatment was followed by a 48- or 72-hour treatment with both drugs together. Asterisk (*) depicts significant difference (P<0.05) of the experimental condition against all the other conditions in the study. Each panel is representative of at least three independent experiments, performed in triplicate wells per condition.