Table 6.
Children with ALRI positive and negative for RSV by multiplex PCR
Variables | RSV positive (n = 50)* | Virus negative (n = 195) | p value | OR (95% CI) |
Median age (Mo) | 10.5 (2–48) | 10 (1–61) | 0.60 | - |
Less than 12 months | 38 | 115 | 0.027 | 2.2 (1.1, 4.5) |
Sex M:F | 35:15 (2.3:1) | 143:52 (2.8:1) | 0.63 | 1.2 (0.55, 2.4) |
Symptoms | ||||
Cough | 49 | 183 | 0.47 | 3.2 (.45, 140.1) |
Difficulty in breathing | 30 | 113 | 0.79 | 1.1 (0.55, 2.2) |
Runny nose | 32 | 70 | 0.001 | 3.2 (1.6, 6.4) |
Sore throat | 0 | 2 | 0.99 | - |
Fever | 44 | 159 | 0.27 | 1.7 (0.64, 5.1) |
Hoarseness | 4 | 6 | 0.12 | 2.7 (0.54, 12.0) |
Asthma | 4 | 7 | 0.24 | 2.3 (0.49, 9.6) |
Grunting | 2 | 5 | 0.63 | 1.6 (0.15, 10.0) |
Nasal flaring | 5 | 18 | 0.86 | 1.1 (0.30, 3.3) |
Stridor | 2 | 5 | 0.63 | 1.6 (0.15, 10.0) |
Chest indrawing | 19 | 80 | 0.69 | 0.88 (0.44, 1.7) |
Cyanosis | 0 | 7 | 0.35 | - |
Recurrent pneumonia | 3 | 15 | 0.99 | 4.1 (0.53, 31.2) |
Pneumonia | 38 | 151 | 0.82 | 0.92 (0.43, 2.1) |
Bronchiolitis | 41 | 42 | 0.001 | 16.6 (7.1, 41.4) |
Risk factors | ||||
ARI in family | 23 | 62 | 0.06 | 1.8 (0.92, 3.6) |
Prematurity | 6 | 13 | 0.20 | 1.9 (0.56, 5.7) |
Smokers in family | 20 | 67 | 0.45 | 1.3 (0.63, 2.5) |
Co-morbidity | 5 | 66 | 0.001 | 0.22 (0.06, 0.59) |
* episodes of co-infection with other viruses were excluded