Figure 3.

Typical hetero-droplet profiles. Here (a1,2) stand for the single (residue i = 6), and (b1,2) represent the double (residue i = 4, 6 with a clustering effect) heterogeneity cases. δV₁/V₁ = (a1) 0.4 (a2) 0.2, and δV₁ = V₂ = (b1) 0.4 (b2) 0.2 V₁ with k_BT/V₁ = 0.19, stand for the strong/mild heterogeneity cases, respectively. Other parameters include n = 10, γ = 3, σ = 1, and ν₀ = 10⁻⁴. The folded residues are indicated by ●. Note that the droplet profiles are kinetically connected by add/dropping a folded residue, and in (b1), the Q = 2 droplet corresponds to four noncontiguous sequence stretches.