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. Author manuscript; available in PMC: 2009 Jul 14.
Published in final edited form as: Aging Cell. 2008 Mar 10;7(3):394–404. doi: 10.1111/j.1474-9726.2008.00385.x

Figure 4. BD suppresses proteotoxicity by a mechanism distinct from insulin/IGF-1 like signaling.

Figure 4

(A) RNAi inhibition of daf-16 significantly accelerates paralysis in Q35YFP animals relative to growth on empty vector bacteria (8.0 × 10−3), but does not prevent suppression of paralysis by BD (p=4.5 × 10−9). (B) RNAi inhibition of daf-2 significantly reduces paralysis in Q35YFP animals relative to growth on EV bacteria (p=7.6 × 10−7). BD further reduces paralysis of daf-2 RNAi treated animals (p=1.0 × 10−14).