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. Author manuscript; available in PMC: 2009 Jul 14.
Published in final edited form as: Aging Cell. 2008 Mar 10;7(3):394–404. doi: 10.1111/j.1474-9726.2008.00385.x

Figure 5. Heat shock factor 1 is required for enhanced thermotolerance and increased life span in response to BD.

Figure 5

(A) Animals carrying a mutant allele of hsf-1, hsf-1(sy441), fail to show increased survival at 38°C when subjected to BD. Error bars are standard error of the mean. (B) BD fails to increase median life span of hsf-1(sy441) animals (p=0.34) but significantly increases the life span of daf-16(mu86) animals (C) RNAi inhibition of hsf-1 prevents life span extension from BD.