Table 1.
Group | Baseline Threshold (μA) | Baseline Latency (sec) | Latency (sec) after treatment |
||
---|---|---|---|---|---|
15 min | 3 hour | 24 hour | |||
Control IgG + Saline | 121 ± 14 | 3.4 ± 0.2 | 3.4 ± 0.1 | 3.5 ± 0.2 | 3.5 ± 0.2 |
Control IgG + Mecamylamine | 110 ± 16 | 2.7 ± 0.2 | 2.7 ± 0.7 | 3.3 ± 0.4 | 2.8 ± 0.3 |
Nic311 80 mg/kg + Saline | 113 ± 15 | 2.7 ± 0.2 | 2.8 ± 0.2 | 2.6 ± 0.2 | 2.8 ± 0.2 |
Nic311 240 mg/kg + Saline | 95 ± 12 | 2.5 ± 0.4 | 2.6 ± 0.3 | 2.5 ± 0.5 | 2.5 ± 0.2 |