FIGURE 3.
Protein microsequence data for the 185-kDa protein recognized by mab 3A3 compared with those reported for the α chains of VLAs 1–5 (Takada et al., 1987b). The rat antigen is similar through the first four residues to other α subunits of the VLAs (underlined). The homology of this α subunit to VLA-1 is evident from the boxed regions. The amino acid sequence for an additional 12 amino acid residues of the 3A3 antigen was found to be Ser-Gly-Pro-Val-Glu-Asp-Met-Phe-Gly-Tyr-Thr-Val. The sequences obtained from two separate preparations of purified protein matched perfectly, indicating no obvious polymorphisms.